Detection of two CAL.20C SARS-CoV-2 variants in Monterrey metropolitan area in Northeast Mexico

SARS-CoV-2 variants of concern (VOC) are a worldwide problem. CAL.20C is considered a VOC and its distribution should be monitored. We detected two CAL.20C variants in Monterrey, Mexico in patients who had no recent travel history. This indicates that this variant is now transmitted locally in Northeast Mexico.